St. Louis City, MO - Population Estimate, Total, Not Hispanic or Latino, Black or African American Alone (5-year estimate) in St. Louis city, MO was 130231.00000 Persons in January of 2022, according to the United States Federal Reserve. Historically, St. Louis City, MO - Population Estimate, Total, Not Hispanic or Latino, Black or African American Alone (5-year estimate) in St. Louis city, MO reached a record high of 170928.00000 in January of 2009 and a record low of 130231.00000 in January of 2022. Trading Economics provides the current actual value, an historical data chart and related indicators for St. Louis City, MO - Population Estimate, Total, Not Hispanic or Latino, Black or African American Alone (5-year estimate) in St. Louis city, MO - last updated from the United States Federal Reserve on May of 2024.