Resident Population in Osceola County, FL was 437.78400 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Osceola County, FL reached a record high of 437.78400 in January of 2023 and a record low of 25.26700 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Osceola County, FL - last updated from the United States Federal Reserve on May of 2024.